Evaluation of wireless stimulation of the endocardium, WiSE, technology for treatment heart failure. (2nd June 2016)

• Record Type: Journal Article
• Authors: Seifert, M.; Butter, C.
• Is Part Of: Expert review of medical devices. Volume 13:Number 6(2016)
• Page Start: 523
• Page End: 531
• Publication Date: 2016-06-02
• Subjects: Cardiac resynchronization therapy implantation -- leadless left ventricular endocardial pacing -- heart failure -- ultrasound energy transfer; Medical instruments and apparatus -- Periodicals; 610.28
• DOI: 10.1080/17434440.2016.1187559
• Languages: English
• ISSNs: 1743-4440

Abstract

ABSTRACT: Introduction : There are several unsolved limitations in delivering cardiac resynchronization therapy. 30-40% of patients fail to have any clinical benefit after 6 months caused by different reasons. Areas covered : Endocardial stimulation rather than conventional epicardial pacing has been shown to: be more physiologically, improve electrical stimulation of the left ventricular, give less dispersion of repolarisation and result in better resynchronization. The Wireless Cardiac Stimulation in Left Ventricle, WiCS-LV, system provides an option for wireless, left ventricular endocardial pacing triggered from a conventional right ventricular pacing spike from a co-implant. Expert commentary : The feasibility of the WiCS-LV system has been successfully demonstrated in a population of failed cardiac resynchronization patients, either failed implantation procedure of a conventional system, non-responder to conventional therapy or upgrade from pacemaker or defibrillator, where a conventional system was not an option. WiCS-LV is innovative technology with promising safety, performance and preliminary efficacy.