A new dimeric anthraquinone from endophytic Talaromyces sp. YE3016. Issue 15 (2nd August 2016)

• Record Type: Journal Article
• Authors: Xie, Xiao-Song; Fang, Xiao-Wei; Huang, Rong; Zhang, Shou-Peng; Wei, Hong-Xia; Wu, Shao-Hua
• Is Part Of: Natural product research. Volume 30:Issue 15(2016)
• Page Start: 1706
• Page End: 1711
• Publication Date: 2016-08-02
• Subjects: Talaromyces sp -- endophytic fungi -- dimeric anthraquinone -- skyrin; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2015.1136888
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new unsymmetrical dimeric anthraquinone, 3-demethyl-3-(2-hydroxypropyl)-skyrin (1 ) was isolated from the solid-state fermentation extract of an endophytic fungal strain Talaromyces sp. YE 3016, together with five known compounds, skyrin (2 ), oxyskyrin (3 ), emodin (4 ), 1, 3, 6-trihydroxy-8-methyl-anthraquinone (5 ) and ergosterol (6 ). The structure of the new compound was elucidated on the basis of spectroscopic analysis. Compounds1–3 exhibited moderate cytotoxic activities against MCF-7 cell line. Abstract :