A reduced-order modeling for efficient design study of artificial valve in enlarged ventricular outflow tracts. Issue 12 (9th September 2016)

• Record Type: Journal Article
• Authors: Caiazzo, A.; Guibert, R.; Vignon-Clementel, I. E.
• Is Part Of: Computer methods in biomechanics and biomedical engineering. Volume 19:Issue 12(2016)
• Page Start: 1314
• Page End: 1318
• Publication Date: 2016-09-09
• Subjects: Device design -- percutaneous pulmonary valve replacement -- proper orthogonal decomposition (POD) -- finite element method -- blood flow CFD -- repaired Tetralogy of Fallot; Biomechanics -- Data processing -- Periodicals; Biomedical engineering -- Periodicals; Biomechanics -- Periodicals; Biomedical Engineering -- methods -- Periodicals; Computing Methodologies -- Periodicals; 612.7
• DOI: 10.1080/10255842.2015.1133811
• Languages: English
• ISSNs: 1025-5842

Abstract

Abstract : A computational approach is proposed for efficient design study of a reducer stent to be percutaneously implanted in enlarged right ventricular outflow tracts (RVOT). The need for such a device is driven by the absence of bovine or artificial valves which could be implanted in these RVOT to replace the absent or incompetent native valve, as is often the case over time after Tetralogy of Fallot repair. Hemodynamics are simulated in the stented RVOT via a reduce order model based on proper orthogonal decomposition, while the artificial valve is modeled as a thin resistive surface. The reduced order model is obtained from the numerical solution on a reference device configuration, then varying the geometrical parameters (diameter) for design purposes. To validate the approach, forces exerted on the valve and on the reducer are monitored, varying with geometrical parameters, and compared with the results of full CFD simulations. Such an approach could also be useful for uncertainty quantification.