Antimicrobial acylphloroglucinols from the leaves of Rhodomyrtus tomentosa. Issue 6 (2nd June 2016)

• Record Type: Journal Article
• Authors: Liu, Hong-Xin; Tan, Hai-Bo; Qiu, Sheng-Xiang
• Is Part Of: Journal of Asian natural products research. Volume 18:Issue 6(2016)
• Page Start: 535
• Page End: 541
• Publication Date: 2016-06-02
• Subjects: Rhodomyrtus tomentosa -- tomentosone C -- myricetin-3, 7, 3′-trimethyl ether 5′-O-β-glucopyranoside -- antimicrobial activity; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2015.1121997
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Phytochemical study on the leaves of Rhodomyrtus tomentosa resulted in the isolation of fourteen compounds including a new acylphloroglucinol, named tomentosone C (1 ), and a new flavonol glycoside, namely myricetin-3, 7, 3′-trimethyl ether-5′- O - β -glucopyranoside (2 ). Their structures were characterized by spectral data interpretation for new structures and in comparison with published data for known compounds. The antimicrobial activity evaluation revealed that1 and the known acylphloroglucinol rhodomyrtone (3 ) exhibited significant antimicrobial activity with MIC 3.66 and 1.83 μg ml −1, respectively, toward Staphylococcus aureus, responsible for the antimicrobial activity observed with the n -hexane and EtOAc-soluble fraction of the ethanol extract of R. tomentosa leaves. Abstract :