Eligibility Criteria for Deep Brain Stimulation in Parkinson's Disease, Tremor, and Dystonia. (3rd May 2016)
- Record Type:
- Journal Article
- Title:
- Eligibility Criteria for Deep Brain Stimulation in Parkinson's Disease, Tremor, and Dystonia. (3rd May 2016)
- Main Title:
- Eligibility Criteria for Deep Brain Stimulation in Parkinson's Disease, Tremor, and Dystonia
- Authors:
- Munhoz, Renato P.
Picillo, Marina
Fox, Susan H.
Bruno, Veronica
Panisset, Michel
Honey, Christopher R.
Fasano, Alfonso - Abstract:
- Abstract: In this review, the available evidence to guide clinicians regarding eligibility for deep brain stimulation (DBS) in the main conditions in which these forms of therapy are generally indicated—Parkinson's disease (PD), tremor, and dystonia—is presented. In general, the literature shows that DBS is effective for PD, essential tremor, and idiopathic dystonia. In these cases, key points in patient selection must include the level of disability and inability to manage symptoms using the best available medical therapy. Results are, however, still not optimal when dealing with other aetiologies, such as secondary tremors and symptomatic dystonia. Also, in PD, issues such as age and neuropsychiatric profile are still debatable parameters. Overall, currently available literature is able to guide physicians on basic aspects of patient selection and indications for DBS; however, a few points are still debatable and controversial. These issues should be refined and clarified in future studies. RÉSUMÉ: Les critères de recevabilité de la stimulation cérébrale profonde dans des cas de maladie de Parkinson, de tremblements et de dystonie. On le sait, la maladie de Parkinson (MP), des tremblements et la dystonie demeurent les principales conditions pour lesquelles la stimulation cérébrale profonde (SCP) est habituellement indiquée. Dans cette étude, nous voulons donc mettre en évidence les preuves scientifiques pouvant orienter les cliniciens dans le choix d'un traitement de SCP.Abstract: In this review, the available evidence to guide clinicians regarding eligibility for deep brain stimulation (DBS) in the main conditions in which these forms of therapy are generally indicated—Parkinson's disease (PD), tremor, and dystonia—is presented. In general, the literature shows that DBS is effective for PD, essential tremor, and idiopathic dystonia. In these cases, key points in patient selection must include the level of disability and inability to manage symptoms using the best available medical therapy. Results are, however, still not optimal when dealing with other aetiologies, such as secondary tremors and symptomatic dystonia. Also, in PD, issues such as age and neuropsychiatric profile are still debatable parameters. Overall, currently available literature is able to guide physicians on basic aspects of patient selection and indications for DBS; however, a few points are still debatable and controversial. These issues should be refined and clarified in future studies. RÉSUMÉ: Les critères de recevabilité de la stimulation cérébrale profonde dans des cas de maladie de Parkinson, de tremblements et de dystonie. On le sait, la maladie de Parkinson (MP), des tremblements et la dystonie demeurent les principales conditions pour lesquelles la stimulation cérébrale profonde (SCP) est habituellement indiquée. Dans cette étude, nous voulons donc mettre en évidence les preuves scientifiques pouvant orienter les cliniciens dans le choix d'un traitement de SCP. En général, les ouvrages scientifiques montrent que la SCP est efficace pour traiter la MP, les tremblements essentiels et la dystonie idiopathique. Dans ces cas, le degré d'invalidité des patients ainsi que leur incapacité à contrôler ou à agir sur leurs symptômes à l'aide du meilleur traitement médical disponible constituent deux aspects clés dans un processus de sélection. Cela dit, les résultats ne sont pas encore concluants lorsqu'on traite d'autres étiologies telles que les tremblements secondaires et la dystonie symptomatique. De plus, l'âge et le profil neuropsychiatrique des patients continuent à représenter des paramètres discutables. En somme, si la littérature scientifique existante peut orienter les médecins quant aux principaux aspects présidant à la sélection des patients et fournir des précisions en matière de SCP, certains aspects demeurent néanmoins discutables et controversés. Voilà pourquoi ces derniers devraient être davantage examinés et clarifiés dans le cadre de travaux subséquents. … (more)
- Is Part Of:
- Canadian journal of neurological sciences. Volume 43:Number 4(2016)
- Journal:
- Canadian journal of neurological sciences
- Issue:
- Volume 43:Number 4(2016)
- Issue Display:
- Volume 43, Issue 4 (2016)
- Year:
- 2016
- Volume:
- 43
- Issue:
- 4
- Issue Sort Value:
- 2016-0043-0004-0000
- Page Start:
- 462
- Page End:
- 471
- Publication Date:
- 2016-05-03
- Subjects:
- deep brain stimulation, -- dystonia, -- essential tremor, -- movement disorders, -- Parkinson's disease, -- surgery, -- tremor
Neurology -- Periodicals
Nervous system -- Surgery -- Periodicals
Electronic journals
616.8 - Journal URLs:
- http://journals.cambridge.org/action/displayJournal?jid=CJN ↗
http://www.cjns.org/home.html ↗
http://cjns.metapress.com/link.asp?id=300307 ↗
http://cjns.metapress.com/openurl.asp?genre=journal&issn=0317-1671 ↗ - DOI:
- 10.1017/cjn.2016.35 ↗
- Languages:
- English
- ISSNs:
- 0317-1671
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- Legaldeposit
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