Acute pancreatitis. Issue 6 (June 2016)

• Record Type: Journal Article
• Authors: Thomasset, Sarah C.; Carter, C Ross
• Is Part Of: Surgery. Volume 34:Issue 6(2016)
• Page Start: 292
• Page End: 300
• Publication Date: 2016-06
• Subjects: Acute pancreatitis -- multi-organ failure -- necrosectomy -- pancreatic necrosis -- severity scoring; Surgery -- Periodicals; Surgery -- Periodicals; Chirurgie -- Périodiques; Thérapeutique -- Périodiques; Electronic journals; 617
• DOI: 10.1016/j.mpsur.2016.03.008
• Languages: English
• ISSNs: 0263-9319

Abstract

Abstract: Acute pancreatitis is a common diagnosis and its incidence may be rising. The most common aetiological agents remain gallstones and alcohol misuse. Eighty per cent of patients will have a mild attack which resolves within a few days without specific treatment. Severe disease is characterized by a significant systemic inflammatory response which may be associated with varying degrees of organ dysfunction. The mortality in patients with multi-organ failure may be as high as 50%. This article reviews the definition, aetiology, pathophysiology, therapeutic strategies and outcomes in light of recent evidence.