New norlignans and flavonoids of Dysosma versipellis. (June 2016)

• Record Type: Journal Article
• Authors: Zheng, Yue; Xie, Yang-Guo; Zhang, Yu; Li, Tao; Li, Hui-Liang; Yan, Shi-Kai; Jin, Hui-Zi; Zhang, Wei-Dong
• Is Part Of: Phytochemistry letters. Volume 16(2016:Jun.)
• Page Start: 75
• Page End: 81
• Publication Date: 2016-06
• Subjects: Dysosma versipellis -- Flavonoid -- Norlignan -- Antibacterial properties; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2016.03.001
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Highlights: Thirty-eight compounds, including two new norlignans and six new flavonoids were isolated from the roots of Dysosma versipellis . Their structures and absolute configuration were established from NMR and CD data. Dysosmaflavones E and F exhibited mild antibacterial activities. Abstract: Two new norlignans, dysosmanorlignans A and B (1–2 ); six new flavonoids, dysosmaflavones A–F (3–8 ); and 30 known compounds (9–38 ) were isolated from the roots of Dysosma versipellis . Their structures were determined by detailed analysis of MS and NMR spectroscopic data. Dysosmaflavones E and F both exhibited mild antibacterial activities against Streptococcus agalactiae, Pseudomonas aeruginosa, and Bacillus subtilis with MIC values ranging from 93.0 to 93.8 μg/mL.