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Catalyst-free synthesis of N-β-hydroxyethyl pyrroles and indoles via a domino [3+2] cycloaddition and ring-opening aromatization process. Issue 22 (27th May 2015)
Record Type:
Journal Article
Title:
Catalyst-free synthesis of N-β-hydroxyethyl pyrroles and indoles via a domino [3+2] cycloaddition and ring-opening aromatization process. Issue 22 (27th May 2015)
Main Title:
Catalyst-free synthesis of N-β-hydroxyethyl pyrroles and indoles via a domino [3+2] cycloaddition and ring-opening aromatization process
Graphical abstract: Abstract: N -β-Hydroxyethyl pyrroles and indoles were constructed from the reaction of trans -4-hydoxyproline or indoline-2-carboxylic acid with electron deficient aldehydes via a domino [3+2] cycloaddition and ring-opening aromatization process under catalyst-free conditions.