Modulation of innate immune response, mucosal parameters and disease resistance in rainbow trout (Oncorhynchus mykiss) upon synbiotic feeding. Issue 1 (July 2015)

• Record Type: Journal Article
• Authors: Hoseinifar, Seyed Hossein; Mirvaghefi, Alireza; Amoozegar, Mohammad Ali; Sharifian, Maryam; Esteban, M. Ángeles
• Is Part Of: Fish & shellfish immunology. Volume 45:Issue 1(2015:Jul.)
• Page Start: 27
• Page End: 32
• Publication Date: 2015-07
• Subjects: Synbiotic -- Rainbow trout -- Innate immune response -- Skin mucus -- Bactericidal activity -- Disease resistance; Fishes -- Immunology -- Periodicals; Shellfish -- Immunology -- Periodicals; Poissons -- Immunologie -- Périodiques; Crustacés -- Immunologie -- Périodiques; 571.9617
• DOI: 10.1016/j.fsi.2015.03.029
• Languages: English
• ISSNs: 1050-4648

Abstract

Abstract: The present study investigates the effects of dietary supplements of galactooligosaccharides (GOS), Pediococcus acidilactici and P. acidilactici + GOS on innate immune response, skin mucus as well as disease resistance of rainbow trout ( Oncorhynchus mykiss ) fingerlings (15.04 ± 0.52 g). After 8 weeks of feeding, several innate immune (lysozyme, alternative complement and respiratory burst activities) and skin mucus parameters (bactericidal activity against Streptococcus faecium, Streptococcus iniae, Serratia marcescens, Staphylococcus aureus and Escherichia coli and mucus protein content) were studied. The results indicated that the three supplemented diet significantly increased innate immune response and skin mucus parameters in rainbow trout. The highest innate immune response, skin mucus activity as well as protein level was observed in synbiotic fed fish. Furthermore, at the end of the feeding experiment, some fish were intraperitoneally injected with Streptococcus iniae to determine the disease resistance. The mortality of fingerlings fed supplemented diet was significantly lower than fish from control group being the lowest mortality recorded in synbiotic fed fish group. Highlights: There is limited information on synbtiotic effects on fish immune response. Dietary synbitoic remarkably increased innate immune response of rainbow trout. Administration of sybiotic elevated skin mucus immune response. Dietary synbiotic improved resistance of rainbow trout against streptococcosis. Combined administration of Pediococcus acidilactici + GOS (synbiotic) showed more efficiency.