Convenient synthesis of functionalized pyrrolo[3, 4-b]pyridines and pyrrolo[3, 4-b]quinolines via three-component reactions. Issue 42 (12th April 2016)

• Record Type: Journal Article
• Authors: Jiang, Yan-Hong; Xiao, Man; Yan, Chao-Guo
• Is Part Of: RSC advances. Volume 6:Issue 42(2016)
• Page Start: 35609
• Page End: 35616
• Publication Date: 2016-04-12
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra03165j
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A simple protocol for convenient construction of pyrrolo[3, 4- b ]pyridine skeleton was successfully developed by base promoted three-component reaction of β-enamino imide, aromatic aldehydes and malononitrile as well as its ester and amide derivatives. Abstract : A simple protocol for convenient construction of pyrrolo[3, 4- b ]pyridine skeleton was successfully developed by base promoted three-component reaction of β-enamino imide, aromatic aldehydes and malononitrile as well as its ester and amide derivatives. The similar three-component reaction of β-enamino imide, aromatic aldehydes and cyclic diketones such as dimedone and cyclohexane-1, 3-dione afforded functionalized pyrrolo[3, 4- b ]quinolines in good yields.