Cryo‐sectioning of mice for whole‐body imaging of drugs and metabolites with desorption electrospray ionization mass spectrometry imaging – a simplified approach. Issue 11 (15th June 2016)

• Record Type: Journal Article
• Authors: Okutan, Seda; Hansen, Harald S.; Janfelt, Christian
• Other Names: Clench Malcolm R. guestEditor.
• Is Part Of: Proteomics. Volume 16:Issue 11/12(2016)
• Page Start: NA
• Page End: NA
• Publication Date: 2016-06-15
• Subjects: Proteins -- Separation -- Periodicals; Bioinformatics -- Periodicals; Proteomics -- Periodicals; Genomes -- Periodicals; Molecular genetics -- Periodicals; 572.605
• DOI: 10.1002/pmic.201670113
• Languages: English
• ISSNs: 1615-9853

Abstract

Abstract : DOI:10.1002/pmic.201500422 Mass spectrometry imaging can be used for highly specific tracking of several compounds in one experiment. The cover shows mass spectrometry images of a mouse dosed intraperitoneally with the antidepressive drug amitriptyline. The signal from an endogenous lipid is displayed in green, the drug is illustrated in red, and one of the drug metabolites is indicated blue. For more details, see research article by Seda Okutan, Harald S. Hansen and Christian Janfelt on page 1633.