Mild C−H/C−C Activation by Z‐Selective Cobalt Catalysis. Issue 26 (4th May 2016)

• Record Type: Journal Article
• Authors: Zell, Daniel; Bu, Qingqing; Feldt, Milica; Ackermann, Lutz
• Is Part Of: Angewandte Chemie international edition. Volume 55:Issue 26(2016)
• Page Start: 7408
• Page End: 7412
• Publication Date: 2016-05-04
• Subjects: C−C cleavage -- C−H activation -- cobalt -- homogeneous catalysis -- stereoselectivity; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201601778
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: Cationic cobalt complexes enable unprecedented cobalt‐catalyzed C−H/C−C functionalizations with unique selectivity features. The versatile cobalt catalyst proved broadly applicable, enabled efficient C−H/C−C cleavage at room temperature, and delivered Z‐alkenes with excellent diastereocontrol. Abstract : Double activation : Challenging C−H/C−C functionalizations were achieved through the use of cobalt catalysis under exceedingly mild reaction conditions. This method leads to the formation of Z alkenes with unique chemo‐ and diastereoselectivity.