Early echocardiographic predictor of heart failure in cerebral arteriovenous malformations. (8th April 2016)

• Record Type: Journal Article
• Authors: Thankavel, Poonam P.; Ramaciotti, Claudio
• Is Part Of: Cardiology in the young. Volume 26:Number 5(2016)
• Page Start: 1008
• Page End: 1012
• Publication Date: 2016-04-08
• Subjects: Arteriovenous malformation, -- congestive heart failure, -- prognostic marker; Pediatric cardiology -- Periodicals; 618.9212
• DOI: 10.1017/S1047951116000305
• Languages: English
• ISSNs: 1047-9511

Abstract

Abstract: Neonatal congestive heart failure in cerebral arteriovenous malformations carries a high risk of mortality. Severe heart failure leading to end-organ dysfunction may be a contraindication to early intervention. Although echocardiographic markers of haemodynamic instability exist, an objective echocardiographic predictor of severe heart failure is not available. We present a ratio of antegrade to retrograde flow in the aortic arch that objectively identifies those at the highest risk of mortality. This measurement can be easily obtained and has prognostic value at presentation, before clinical deterioration. Outcomes remain poor even when early intervention is offered, which may reflect irreversible neurological abnormalities.