Disseminated mucormycosis with myocardial involvement in a renal transplant recipient. Issue 6 (5th November 2015)

• Record Type: Journal Article
• Authors: Nam, Y.; Jung, J.; Park, S.S.; Kim, S.J.; Shin, S.J.; Choi, J.H.; Kim, M.; Yoon, H.E.
• Is Part Of: Transplant infectious disease. Volume 17:Issue 6(2016)
• Page Start: 890
• Page End: 896
• Publication Date: 2015-11-05
• Subjects: mucormycosis -- renal transplantation -- myocardial abscess; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12452
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: We report the case of a renal transplant recipient with pulmonary and splenic mucormycosis whose demise was accelerated by a myocardial abscess. Once pulmonary and splenic mucormycosis was diagnosed, liposomal amphotericin B was started and immunosuppressant treatments were discontinued. The pulmonary cavities regressed during treatment, but new myocardial and peri‐allograft abscesses developed. The myocardial abscess diffusely infiltrated the left ventricular wall and was associated with akinesia, which led to sudden cardiac arrest. This case demonstrates a rare manifestation of mucormycosis and highlights the fatality and invasiveness of this infection.