Recurrent sequence exchange between homeologous grass chromosomes. (November 2015)

• Record Type: Journal Article
• Authors: Wicker, Thomas; Wing, Rod A.; Schubert, Ingo
• Is Part Of: Plant journal. Volume 84:Number 4(2015:Nov.)
• Page Start: 747
• Page End: 759
• Publication Date: 2015-11
• Subjects: inter‐homeolog recombination -- reciprocal translocation -- whole‐genome duplication -- grass ancestor -- genome evolution; Plant molecular biology -- Periodicals; Plant cells and tissues -- Periodicals; Botany -- Periodicals; 580
• DOI: 10.1111/tpj.13040
• Languages: English
• ISSNs: 0960-7412

Abstract

Summary: All grass species evolved from an ancestor that underwent a whole‐genome duplication (WGD) approximately 70 million years ago. Interestingly, the short arms of rice chromosomes 11 and 12 (and independently their homologs in sorghum) were found to be much more similar to each other than other homeologous regions within the duplicated genome. Based on detailed analysis of rice chromosomes 11 and 12 and their homologs in seven grass species, we propose a mechanism that explains the apparently 'younger' age of the duplication in this region of the genome, assuming a small number of reciprocal translocations at the chromosome termini. In each case the translocations were followed by unbalanced transmission and subsequent lineage sorting of the involved chromosomes to offspring. Molecular dating of these translocation events also allowed us to date major chromosome 'fusions' in the evolutionary lineages that led to Brachypodium and Triticeae. Furthermore, we provide evidence that rice is exceptional regarding the evolution of chromosomes 11 and 12, inasmuch as in other species the process of sequence exchange between homeologous chromosomes ceased much earlier than in rice. We presume that random events rather than selective forces are responsible for the observed high similarity between the short arm ends of rice chromosomes 11 and 12. Significance Statement: The ancestor of extant grass species underwent a whole‐genome duplication 70 million years ago, but surprisingly two rice chromosomes seemed to contradict this age. Here we propose that reciprocal translocations at the chromosome termini, followed by unbalanced transmission of these chromosomes, explains the apparent younger age of the whole genome duplication in these chromosomal regions.