Sysmex XT‐2000iV scattergram analysis in a cat with basophilia. (26th February 2016)

• Record Type: Journal Article
• Authors: Stranieri, Angelica; Ferrari, Roberta; Zanzani, Sergio; Rossi, Gabriele
• Is Part Of: Veterinary clinical pathology. Volume 45:Number 2(2016)
• Page Start: 225
• Page End: 228
• Publication Date: 2016-02-26
• Subjects: Differential leukocyte count -- lysis‐resistant granulocytes -- feline blood -- laser counter; Veterinary pathology -- Periodicals; 636.089607
• DOI: 10.1111/vcp.12340
• Languages: English
• ISSNs: 0275-6382

Abstract

Abstract: A 13‐year‐old female Domestic Shorthair cat was presented to the Veterinary Teaching Hospital of the University of Milan for an interscapular mass suspected to be a mesenchymal malignant tumor. A preoperative CBC performed with Sysmex XT‐2000iV showed leukocytosis with neutrophilia and eosinophilia. The Sysmex WBC/DIFF scattergram showed an additional, well‐separated cluster of events between the neutrophil, eosinophil, and lymphocyte clusters. Blood smear evaluation revealed the presence of a significant number of basophils; thus, it was hypothesized that the additional cluster could represent the basophilic population. A second CBC, 24 days later, showed the same pattern on the WBC/DIFF scattergram in the absence of leukocytosis and neutrophilia. After surgical excision of the mass, a definitive diagnosis of feline injection site sarcoma was made. To the author's knowledge, there are no previous reports about the identification of feline basophils in the WBC/DIFF scattergram of Sysmex XT‐2000iV.