Consensus, Dilemmas, and Challenges in Living Donor Liver Transplantation in Latin America. Issue 6 (June 2016)

• Record Type: Journal Article
• Authors: Salvalaggio, Paolo R.; Seda Neto, João; Alves, Jefferson Andre; Fonseca, Eduardo A.; Carneiro de Albuquerque, Luiz; Andraus, Wellington; Massarollo, Paulo B.; Duro Garcia, Valter; Maurette, Rafael J.; Ruf, Andrés E.; Pacheco-Moreira, Lucio F.; Caicedo Rusca, Luis A.; Osorio, Veronica Botero; Matamoros, Maria Amalia; Varela-Fascinetto, Gustavo; Jarufe, Nicolas P.
• Is Part Of: Transplantation. Volume 100:Issue 6(2016)
• Publication Date: 2016-06
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; Transplantation immunology -- Periodicals; 617.95
• DOI: 10.1097/TP.0000000000001180
• Languages: English
• ISSNs: 0041-1337

Abstract

Abstract : Abstract: We reviewed the history, volume, outcomes, uniqueness, and challenges of living donor liver transplantation (LDLT) in Latin America. We used the data from the Latin American and Caribbean Transplant Society, local transplant societies, and opinions from local transplant experts. There are more than 160 active liver transplant teams in Latin America, but only 30 centers have used LDLT in the past 2 years. In 2014, 226 LDLTs were done in the region (8.5% of liver transplant activities). Living donor liver transplantation is mainly restricted to pediatric patients. Adult-to-adult LDLT activities decreased after the implementation of the model for end-stage liver disease score and a concomitant increase on the rate of deceased donors per million population. Posttransplant outcome analysis is not mandatory, transparent or regulated in most countries. More experienced teams have outcomes comparable to international expert centers, but donor and recipient morbidity might be underreported. Latin America lags behind in terms of the number of adult LDLT and the rate of living donor utilization in comparison with other continents with similar donation rates. Local alliances and collaborations with major transplant centers in the developed world will contribute to the development of LDLT in Latin America.