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ChemInform Abstract: Diastereoselective Synthesis of Tetrasubstituted Propargylamines via Hydroamination and Metalation of 1‐Alkynes and Their Enantioselective Conversion to Trisubstituted Chiral Allenes. Issue 25 (June 2016)
Record Type:
Journal Article
Title:
ChemInform Abstract: Diastereoselective Synthesis of Tetrasubstituted Propargylamines via Hydroamination and Metalation of 1‐Alkynes and Their Enantioselective Conversion to Trisubstituted Chiral Allenes. Issue 25 (June 2016)
Main Title:
ChemInform Abstract: Diastereoselective Synthesis of Tetrasubstituted Propargylamines via Hydroamination and Metalation of 1‐Alkynes and Their Enantioselective Conversion to Trisubstituted Chiral Allenes.
Abstract: The reactions involve the diastereoselective addition of in situ formed alkynylcopper complexes to in situ formed iminium ions regioselectively affording the corresponding propargylamines.