Synthesis of isotopically labelled 2‐isopropylthioxanthone from 2, 2′‐dithiosalicylic acid and deuterium cumene. (28th April 2016)

• Record Type: Journal Article
• Authors: Fang, Chao; Yang, Weicheng; Yang, Chao; Wang, Haoran; Sun, Kai; Luo, Yong
• Is Part Of: Journal of labelled compounds & radiopharmaceuticals. Volume 59:Number 8(2016)
• Page Start: 313
• Page End: 316
• Publication Date: 2016-04-28
• Subjects: 2‐isopropylthioxanthone -- labelled internal standards -- two synthetic routes -- deuterium cumene; Tracers (Chemistry) -- Periodicals; Radiopharmaceuticals -- Periodicals; 615.8424
• DOI: 10.1002/jlcr.3400
• Languages: English
• ISSNs: 0362-4803

Abstract

Abstract : Two efficient synthetic routes of stable deuterium labelled 2‐isopropylthioxanthone were presented with 98.1% and 98.8% isotopic abundance in acceptable yields and excellent chemical purities. Their structures and the isotope‐abundance were confirmed according to proton nuclear magnetic resonance and liquid chromatography–mass spectrometry. Abstract : Two efficient synthetic routes of stable deuterium labelled 2‐isopropylthioxanthone were presented with 98.1% and 98.8% isotopic abundance in acceptable yields and excellent chemical purities.