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ChemInform Abstract: Rhodium‐Catalyzed Tandem C—H Activation and Aza‐Michael Addition of 2‐Arylquinazolin‐4‐ones with Acrylates for the Synthesis of Pyrrolo[2, 1‐b]quinazolin‐9(1H)‐one Derivatives. Issue 25 (June 2016)
Record Type:
Journal Article
Title:
ChemInform Abstract: Rhodium‐Catalyzed Tandem C—H Activation and Aza‐Michael Addition of 2‐Arylquinazolin‐4‐ones with Acrylates for the Synthesis of Pyrrolo[2, 1‐b]quinazolin‐9(1H)‐one Derivatives. Issue 25 (June 2016)
Main Title:
ChemInform Abstract: Rhodium‐Catalyzed Tandem C—H Activation and Aza‐Michael Addition of 2‐Arylquinazolin‐4‐ones with Acrylates for the Synthesis of Pyrrolo[2, 1‐b]quinazolin‐9(1H)‐one Derivatives.
Abstract: A tandem C—H activation/aza‐Michael reaction of quinazolinones (I) with acrylic esters is achieved in the presence of a dual Rh/Ag‐catalyst to provide pyrrolo[2.1‐b]quinazolin‐9(1H)‐ones in good to excellent yields.