This is an interim version of our Electronic Legal Deposit Catalogue-eJournals and eBooks while we continue to recover from a cyber-attack.
ChemInform Abstract: Synthesis of Tetra‐Substituted 5‐Trifluoromethylpyrazoles via Sequential Halogenation/Palladium‐Catalyzed C—C and C—N Cross‐Coupling. Issue 25 (June 2016)
Record Type:
Journal Article
Title:
ChemInform Abstract: Synthesis of Tetra‐Substituted 5‐Trifluoromethylpyrazoles via Sequential Halogenation/Palladium‐Catalyzed C—C and C—N Cross‐Coupling. Issue 25 (June 2016)
Main Title:
ChemInform Abstract: Synthesis of Tetra‐Substituted 5‐Trifluoromethylpyrazoles via Sequential Halogenation/Palladium‐Catalyzed C—C and C—N Cross‐Coupling.
Abstract: The new synthetically useful methodology to construct tetrasubstituted trifluoromethylpyrazoles involves halogenation of starting trifluoromethylpyrazoles, and subsequent palladium‐catalyzed Negishi coupling or Buchwald‐Hartwig amination with (hetero)arylzinc chlorides and primary alkylamines.