The OPTN Deceased Donor Potential Study: Implications for Policy and Practice. Issue 6 (10th March 2016)

• Record Type: Journal Article
• Authors: Klassen, D. K.; Edwards, L. B.; Stewart, D. E.; Glazier, A. K.; Orlowski, J. P.; Berg, C. L.
• Other Names: McCleary Karl J investigator.; Hirsch Gary B investigator.; Boulware L. Ebony investigator.; King Gary investigator.; Myer Kevin A investigator.; Reibel Michael investigator.; Rosendale John D investigator.; Saeed Khalid investigator.; Siminoff Laura A investigator.; Soret Samuel investigator.; Wagstaff David A investigator.; Wile Kristina investigator.; Essien Joyce D K investigator.; Crandall Betty C investigator.; Cornell Danielle L investigator.; Jacobs David G investigator.; Bosch David W investigator.; Howard David H investigator.; Faulkner Dorothy L investigator.; Bergstrom George F investigator.; Rushton Gerald investigator.; Franklin Glen investigator.; Wilkins Harry E investigator.; Rahmandad Hazhir investigator.; Nathan Howard M investigator.; Tuttle‐Newhall J Elizabeth investigator.; Wynn James J investigator.; Whaley Janice investigator.; Perryman Jennie P investigator.; Schold Jesse investigator.; Belcher John investigator.; Mayglothing Julie A investigator.; Garcia Karen investigator.; O'Conner Kevin J investigator.; Kyckholm Laurie J investigator.; Ohler Linda investigator.; Markham Lori E investigator.; Sastry M Anjali investigator.; Farinelli Fierro Marcella investigator.; DeLauro Maria investigator.; Kelleher‐Crabtree Mary investigator.; Johnson Maryl R investigator.; Rogers Meg M investigator.; Pyrsopoulos Nikolaos T investigator.; Geraghty P J investigator.; Halverson Paul K investigator.; Bennett Renee investigator.; Hasz Richard D investigator.; Higgins Robert S D investigator.; Youngner Stuart J investigator.; Conrad Suzanne Lane investigator.; Mone Thomas investigator.; Nakagawa Thomas A investigator.; Bleck Thomas P investigator.; Pruett Timothy L investigator.; Durbin Richard investigator.; McLaughlin Christopher J investigator.; Belgay Teresa M investigator.; Shepard Brian investigator.;
• Is Part Of: American journal of transplantation. Volume 16:Issue 6(2016:Jun.)
• Page Start: 1707
• Page End: 1714
• Publication Date: 2016-03-10
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ajt.13731
• Languages: English
• ISSNs: 1600-6135

Abstract

Abstract : The Organ Procurement and Transplantation Network (OPTN) Deceased Donor Potential Study, funded by the Health Resources and Services Administration, characterized the current pool of potential deceased donors and estimated changes through 2020. The goal was to inform policy development and suggest practice changes designed to increase the number of donors and organ transplants. Donor estimates used filtering methodologies applied to datasets from the OPTN, the National Center for Health Statistics, and the Agency for Healthcare Research and Quality and used these estimates with the number of actual donors to estimate the potential donor pool through 2020. Projected growth of the donor pool was 0.5% per year through 2020. Potential donor estimates suggested unrealized donor potential across all demographic groups, with the most significant unrealized potential (70%) in the 50–75‐year‐old age group and potential Donation after Circulatory Death (DCD) donors. Actual transplants that may be realized from potential donors in these categories are constrained by confounding medical comorbidities not identified in administrative databases and by limiting utilization practices for organs from DCD donors. Policy, regulatory, and practice changes encouraging organ procurement and transplantation of a broader population of potential donors may be required to increase transplant numbers in the United States. Abstract : Findings from the OPTN Deceased Donor Potential Study suggest possible transplant center and organ procurement organization practice changes, as well as potential transplant system regulatory changes, which may expand the donor pool.