Ascorbic acid promoted [4 + 2] benzannulation: a mild, operationally simple approach to the synthesis of phenanthrenes. Issue 5 (29th March 2016)

• Record Type: Journal Article
• Authors: Bu, Mei-jie; Lu, Guo-ping; Cai, Chun
• Is Part Of: Organic chemistry frontiers. Volume 3:Issue 5(2016:May.)
• Page Start: 630
• Page End: 634
• Publication Date: 2016-03-29
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c6qo00020g
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : Ascorbic acid-promoted radical [4 + 2] benzannulation for the generation of substituted phenanthrenes at room temperature has been developed. Abstract : A mild, simple and metal-free radical [4 + 2] benzannulation for the generation of phenanthrenes has been developed. A substoichiometric reductant, ascorbic acid (vitamin C), is harnessed as the radical initiator. This method has a broad substrate scope, and various substituted phenanthrenes were obtained in moderate to good yields at room temperature without irradiation.