Catalytic Enantioselective 1, 2‐Addition of Terminal 1, 3‐Diynes to Trifluoromethyl Ketones. Issue 5 (14th March 2016)
- Record Type:
- Journal Article
- Title:
- Catalytic Enantioselective 1, 2‐Addition of Terminal 1, 3‐Diynes to Trifluoromethyl Ketones. Issue 5 (14th March 2016)
- Main Title:
- Catalytic Enantioselective 1, 2‐Addition of Terminal 1, 3‐Diynes to Trifluoromethyl Ketones
- Authors:
- Zheng, Yan
Ma, Hai
Ma, Jun‐An - Abstract:
- Abstract: A facile catalytic enantioselective 1, 2‐addition of diynes to trifluoromethyl ketones was developed. By a combination of Me2 Zn, Ti(OPr‐ i )4, BaF2 and quinine, the reaction of a series of terminal diynes with trifluoromethyl ketones proceeded to afford trifluoromethylated chrial tertiary alcohols with the diyne moiety in good to high yields with moderate to high enantioselectivities. Furthermore, this catalytic asymmetric diyne addition to trifluoromethylketone was applied in the synthesis of the Efavirenz analogue. Abstract :
- Is Part Of:
- Chinese journal of chemistry. Volume 34:Issue 5(2016:May)
- Journal:
- Chinese journal of chemistry
- Issue:
- Volume 34:Issue 5(2016:May)
- Issue Display:
- Volume 34, Issue 5 (2016)
- Year:
- 2016
- Volume:
- 34
- Issue:
- 5
- Issue Sort Value:
- 2016-0034-0005-0000
- Page Start:
- 511
- Page End:
- 518
- Publication Date:
- 2016-03-14
- Subjects:
- 1, 3‐diyne -- trifluoromethyl ketone -- 1, 2‐addition -- enantioselectivity -- asymmetric catalysis
Chemistry -- Periodicals
540.5 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1614-7065 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/cjoc.201500901 ↗
- Languages:
- English
- ISSNs:
- 1001-604X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3180.299500
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1931.xml