Asymmetric Organocatalytic Assembly of Oxindoles Fused with Spiro‐3, 4‐dihydropyrans with Three Contiguous Stereocenters Consisting of Vicinal Quaternary Centers. Issue 5 (16th March 2016)

• Record Type: Journal Article
• Authors: Vishwanath, Manjunatha; Vinayagam, Poopathy; Gajulapalli, V Pratap Reddy; Kesavan, Venkitasamy
• Is Part Of: Asian journal of organic chemistry. Volume 5:Issue 5(2016)
• Page Start: 613
• Page End: 616
• Publication Date: 2016-03-16
• Subjects: bifunctional thioureas -- bispiro-3, 4-dihydropyrans -- cycloaddition -- organocatalysis -- spirooxindoles; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.201600051
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: Diverse bispiro‐3, 4‐dihydropyrans consisting of oxindole moieties with three contiguous chiral centers and vicinal quaternary stereocenters were synthesized with very good yields of up to 92 % and excellent enantioselectivity of up to 99 % ee by using a proline‐derived thiourea organocatalyst. Abstract : The numbers don't lie : Diverse bispiro‐3, 4‐dihydropyrans consisting of oxindole moieties with three contiguous chiral centers and vicinal quaternary stereocenters were synthesized with very good yields of up to 92 % and excellent enantioselectivity of up to 99 % ee by using a proline‐derived thiourea organocatalyst.