Outside front cover: Differential proteome and cellular adhesion analyses of the probiotic bacterium Lactobacillus acidophilus NCFM grown on raffinose – an emerging prebiotic. Issue 9 (May 2016)

• Record Type: Journal Article
• Authors: Celebioglu, Hasan U.; Ejby, Morten; Majumder, Avishek; Købler, Carsten; Goh, Yong J.; Thorsen, Kristian; Schmidt, Bjarne; O'Flaherty, Sarah; Hachem, Maher A.; Lahtinen, Sampo J.; Jacobsen, Susanne; Klaenhammer, Todd R.; Brix, Susanne; Mølhave, Kristian; Svensson, Birte
• Is Part Of: Proteomics. Volume 16:Issue 9(2016)
• Page Start: NA
• Page End: NA
• Publication Date: 2016-05
• Subjects: Proteins -- Separation -- Periodicals; Bioinformatics -- Periodicals; Proteomics -- Periodicals; Genomes -- Periodicals; Molecular genetics -- Periodicals; 572.605
• DOI: 10.1002/pmic.201670090
• Languages: English
• ISSNs: 1615-9853

Abstract

Abstract : DOI:10.1002/pmic.201500212 Lactobacillus acidophilus NCFM is a commonly used and well‐studied probiotic bacterium. By the present differential proteome analysis, new insights into its synbiotic combination with the emerging prebiotic raffinose through comparative whole‐cell and surface proteomes coupled with intestinal cell adhesion analysis are gained. This picture shows bacterial cells adhering to human colonic HT‐29 cells as stimulated by raffinose (chemical formula) and the representative 2‐DIGE image of bacterial proteins with increased (red) and reduced abundance (green) identified by mass spectrometry. For details, see research article by Hasan U. Celebioglu et al., on page 1361