A one pot, metal-free, three-component domino sequence for the synthesis of furans: an efficient C–O and C–N bond formation approach. Issue 46 (20th April 2016)

• Record Type: Journal Article
• Authors: Guo, Pengfeng; Wang, Changcheng; Chen, Ya; Ou, Caijun; Jiang, Hangqi; Chen, Weifeng; Chen, Weixin; Cao, Hua
• Is Part Of: RSC advances. Volume 6:Issue 46(2016)
• Page Start: 39563
• Page End: 39567
• Publication Date: 2016-04-20
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra05815a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A novel one pot, metal-free, three-component domino reaction for the formation of furan derivatives has been developed from 3-phenylpropiolaldehyde, 1, 3-dicarbonyl compounds and aromatic amine or aliphatic acid. Abstract : A novel one pot, metal-free, three-component domino reaction for the formation of furan derivatives has been developed from 3-phenylpropiolaldehyde, 1, 3-dicarbonyl compounds and aromatic amine or aliphatic acid. This transformation provided a general and facile access to the construction of C–O and C–N bonds to prepare various bioactive furans in good yields.