The effect of glassing solvent deuteration and Gd3+ doping on 13C DNP at 5 T. Issue 45 (19th April 2016)

• Record Type: Journal Article
• Authors: Kiswandhi, Andhika; Lama, Bimala; Niedbalski, Peter; Goderya, Mudrekh; Long, Joanna; Lumata, Lloyd
• Is Part Of: RSC advances. Volume 6:Issue 45(2016)
• Page Start: 38855
• Page End: 38860
• Publication Date: 2016-04-19
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra02864k
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : We report the influence of glassing solvent deuteration and Gd 3+ doping on 13 C dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) performed on [1- 13 C] sodium acetate at B 0 = 5 T and 1.2 K. Abstract : We report the influence of glassing solvent deuteration and Gd 3+ doping on 13 C dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) performed on [1- 13 C] sodium acetate at B 0 = 5 T and 1.2 K. Our data reveal that at 5 T, glassing solvent deuteration still results in a 40% improvement of the 13 C DNP signal when a large electron spin resonance (ESR) linewidth 4-oxo-TEMPO free radical is used, but results in a 60% decrease of the DNP signal in the case of a sample doped with small ESR linewidth trityl OX063. An addition of a trace amount of the Gd 3+ complex Gd–HP–DO3A led to a negligible slight decrease on the 13 C polarization TEMPO-doped sample, but is still relatively beneficial for the trityl-doped sample with 30% improvement of the DNP-enhanced 13 C polarization. These findings indicate that while these DNP optimization steps are still valid at 5 T, the effects are not as pronounced as observed in 13 C DNP at B 0 = 3.35 T. These DNP results at 5 T are discussed thermodynamically within the framework of the thermal mixing model of DNP.