Efficient visualization of H2S via a fluorescent probe with three electrophilic centres. Issue 15 (31st March 2016)

• Record Type: Journal Article
• Authors: Asthana, Sharad Kumar; Kumar, Ajit; Neeraj, ; Shweta, ; Upadhyay, K. K.
• Is Part Of: Organic & biomolecular chemistry. Volume 14:Issue 15(2016)
• Page Start: 3690
• Page End: 3694
• Publication Date: 2016-03-31
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c6ob00197a
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A meticulous design strategy of incorporating three electrophilic centres in an optical probe (FLA ) led to the achievement of high sensitivity and rapid response time (40 s) towards H2 S detection. Abstract : H2 S is a reactive nucleophilic species with toxic effects towards human beings. Its efficient detection and marking is still a challenging job due to its similar nucleophilic character to a number of biothiols, like glutathione, cysteine, homocysteine etc . We report herein the first ever use of a chemosensor incorporating three electrophilic centres to achieve high sensitivity and very fast response time (40 s) towards H2 S.