Calcium oxalate precipitation by diffusion using laminar microfluidics: toward a biomimetic model of pathological microcalcifications. Issue 7 (14th March 2016)

• Record Type: Journal Article
• Authors: Laffite, G.; Leroy, C.; Bonhomme, C.; Bonhomme-Coury, L.; Letavernier, E.; Daudon, M.; Frochot, V.; Haymann, J. P.; Rouzière, S.; Lucas, I. T.; Bazin, D.; Babonneau, F.; Abou-Hassan, A.
• Is Part Of: Lab on a chip. Volume 16:Issue 7(2016)
• Page Start: 1157
• Page End: 1160
• Publication Date: 2016-03-14
• Subjects: Miniature electronic equipment -- Periodicals; Combinatorial chemistry -- Periodicals; Biotechnology -- Periodicals; 543.0813
• DOI: 10.1039/c6lc00197a
• Languages: English
• ISSNs: 1473-0197

Abstract

Abstract : The effect of mixing calcium and oxalate precursors by diffusion at miscible liquid interfaces on CaOx crystalline phases is studied using a microfluidic channel. Abstract : The effect of mixing calcium and oxalate precursors by diffusion at miscible liquid interfaces on calcium oxalate crystalline phases, and in physiological conditions (concentrations and flow rates), is studied using a microfluidic channel. This channel has similar dimensions as the collection duct in human kidneys and serves as a biomimetic model in order to understand the formation of pathological microcalcifications.