Copper-mediated C(sp3)–H azidation with Me3SiN3: synthesis of imidazoles from ketones and aldehydes. Issue 38 (21st April 2016)
- Record Type:
- Journal Article
- Title:
- Copper-mediated C(sp3)–H azidation with Me3SiN3: synthesis of imidazoles from ketones and aldehydes. Issue 38 (21st April 2016)
- Main Title:
- Copper-mediated C(sp3)–H azidation with Me3SiN3: synthesis of imidazoles from ketones and aldehydes
- Authors:
- Xie, Zeqiang
Deng, Jiaojiao
Qiu, Zhiping
Li, Juan
Zhu, Qiang - Abstract:
- Abstract : The efficient construction of 2, 4, 5-trisubstituted imidazoles, through a copper-mediated three-component reaction involving ketones, aldehydes, and Me3 SiN3, has been developed. Abstract : The efficient construction of 2, 4, 5-trisubstituted imidazoles, through a copper-mediated three-component reaction involving ketones, aldehydes, and Me3 SiN3, has been developed. During the process, 4 C–N bonds were formed sequentially. Experimental results and DFT calculations suggested that azidation of the alpha methylene group of the ketone was the key C–N bond-forming step.
- Is Part Of:
- Chemical communications. Volume 52:Issue 38(2016)
- Journal:
- Chemical communications
- Issue:
- Volume 52:Issue 38(2016)
- Issue Display:
- Volume 52, Issue 38 (2016)
- Year:
- 2016
- Volume:
- 52
- Issue:
- 38
- Issue Sort Value:
- 2016-0052-0038-0000
- Page Start:
- 6467
- Page End:
- 6470
- Publication Date:
- 2016-04-21
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6cc01863g ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 2722.xml