An optimal hydrogen-bond surrogate for α-helices. Issue 33 (5th April 2016)
- Record Type:
- Journal Article
- Title:
- An optimal hydrogen-bond surrogate for α-helices. Issue 33 (5th April 2016)
- Main Title:
- An optimal hydrogen-bond surrogate for α-helices
- Authors:
- Joy, Stephen T.
Arora, Paramjit S. - Abstract:
- Abstract : The manuscript describes the impact of alkene-derived hydrogen bond isosteres on the stability of constrained helices. Abstract : Substitution of a main chain i → i + 4 hydrogen bond with a covalent bond can nucleate and stabilize the α-helical conformation in peptides. Herein we describe the potential of different alkene isosteres to mimic intramolecular hydrogen bonds and stabilize α-helices in diverse peptide sequences.
- Is Part Of:
- Chemical communications. Volume 52:Issue 33(2016)
- Journal:
- Chemical communications
- Issue:
- Volume 52:Issue 33(2016)
- Issue Display:
- Volume 52, Issue 33 (2016)
- Year:
- 2016
- Volume:
- 52
- Issue:
- 33
- Issue Sort Value:
- 2016-0052-0033-0000
- Page Start:
- 5738
- Page End:
- 5741
- Publication Date:
- 2016-04-05
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6cc01104g ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 934.xml