Visible-light-initiated difluoromethylation of arene diazonium tetrafluoroborates. Issue 35 (8th April 2016)

• Record Type: Journal Article
• Authors: Wu, Ye-bin; Lu, Guo-ping; Zhou, Bao-jing; Bu, Mei-jie; Wan, Li; Cai, Chun
• Is Part Of: Chemical communications. Volume 52:Issue 35(2016)
• Page Start: 5965
• Page End: 5968
• Publication Date: 2016-04-08
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc00177g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A mild and efficient method for the radical addition of α-aryl-β, β-difluoroenol silyl with arene diazonium tetrafluoroborates at room temperature has been disclosed. Abstract : A mild and efficient method for the radical addition of α-aryl-β, β-difluoroenol silyl with arene diazonium tetrafluoroborates at room temperature has been disclosed, which involves an innate radical long chain cycle, so only a small amount (0.05 mol%) of photocatalyst and a short light exposure time are required as radical initiators. A proposed mechanism for the transformation is also illustrated based on the results of control experiments and quantum calculations. A variety of α-aryl-α, α-difluoroketones were formed in moderate to high yields, and can be easily further transformed into various difluoromethylarenes under basic conditions.