Isomer differentiation through supramolecular self-assembly in microdroplets of milliseconds life-time. Issue 5 (3rd February 2016)

• Record Type: Journal Article
• Authors: Qiu, Ran; Sun, Jiamu; Zhang, Xin; Zhao, Wenbo; Qin, Zhen; Luo, Hai
• Is Part Of: Analyst. Volume 141:Issue 5(2016)
• Page Start: 1641
• Page End: 1644
• Publication Date: 2016-02-03
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/c6an00076b
• Languages: English
• ISSNs: 0003-2654

Abstract

Abstract : Supramolecular self-assembly in microdroplets with life-time of milliseconds. Abstract : Supramolecular recognition of thymine (or its analogs) with various central cations can form magic number clusters. Dual nano-ESI via theta tip emitters was used to on-line synthesize clusters. Even thermodynamically unstable clusters can be detected by MS thanks to the very short life-time (∼ms) of the generated microdroplets. By recording characteristic cluster distributions, isomers can be clearly differentiated in a novel "bottom-up" way. Theoretical calculations were performed to explain the MS results.