Cardiovascular surveillance in breast cancer treatment: A more individualized approach is needed. (July 2016)

• Record Type: Journal Article
• Authors: Maas, Angela H.E.M.; Ottevanger, Nelleke; Atsma, Femke; Cramer, Maarten J.; Leiner, Tim; Poortmans, Philip
• Is Part Of: Maturitas. Volume 89(2016)
• Page Start: 58
• Page End: 62
• Publication Date: 2016-07
• Subjects: ACE angiotensin converting enzyme inhibitors -- AI aromatase inhibitors -- BC breast cancer -- DCIS ductal carcinoma in situ -- CVD cardiovascular disease -- ESC European society of cardiology -- GLS global longitudinal strain -- HFpEF heart failure with preserved ejection fraction -- LV left ventricular -- SERM selective estrogen receptor modulator -- VEGF vascular endothelial growth factor -- VTE venous thrombotic even; Breast cancer -- Cardiotoxicity -- Cardiovascular toxicity -- Cardiosurveillance; Climacteric -- Periodicals; Menopause -- Periodicals; Climacteric -- Periodicals; Geriatrics -- Periodicals; Menopause -- Periodicals; Middle Aged -- Periodicals; Climatère -- Périodiques; Ménopause -- Périodiques; Climacterium; Climacteric; Menopause; Electronic journals; Periodicals; 612.66
• DOI: 10.1016/j.maturitas.2016.04.015
• Languages: English
• ISSNs: 0378-5122

Abstract

Highlights: While breast cancer treatment is targeted more on tumor and patient characteristics, a tailored individual approach with early and late cardiosurveillance is not yet implemented in routine care. Newly available cardiac imaging techniques are better suited for the early detection of cardiotoxicity and should be used more often in those patients at highest risk. There is an urgent need for a more tailored patient approach to prevent (early) irreversible cardiac damage by cancer treatment. Abstract: Newly developed treatment strategies for breast cancer have reduced mortality rates over the past decades. Patients with breast cancer represent a heterogeneous population. Differences in the severity of the disease require diverse treatment options. Women have distinct individual risk patterns for cardiovascular disease that may affect their susceptibility to cardiotoxicity during therapy. While breast cancer treatment is targeted more on tumor and patient characteristics, a tailored individual approach with early and late cardiosurveillance is not yet implemented in routine care. Newly available cardiac imaging techniques are better suited to the early detection of cardiotoxicity and should be used more often in those patients at highest risk, as the early intervention afforded will improve their quality of life and prognosis.