Timing of breast cancer surgery, menstrual phase, and prognosis: Systematic review and meta-analysis. (June 2016)

• Record Type: Journal Article
• Authors: Klonoff-Cohen, Hillary; An, Ruopeng; Fries, Theodora; Le, Jennifer; Matt, Georg E.
• Is Part Of: Critical reviews in oncology/hematology. Volume 102(2016)
• Page Start: 1
• Page End: 14
• Publication Date: 2016-06
• Subjects: ND no data -- MR medical record -- LMP last menstrual period -- L luteal -- F follicular -- D days -- EF early follicular -- LF late follicular -- EL early luteal -- ML middle luteal -- LL late luteal -- PO periovulatiory -- PM perimenstrual -- PR proliferative -- S secretory -- RO reoccurrence -- BF breastfeeding; Breast cancer -- Luteal phase -- Menstrual cycle -- Premenopausal -- Surgery; Oncology -- Periodicals; Hematology -- Periodicals; 616.994
• DOI: 10.1016/j.critrevonc.2016.02.004
• Languages: English
• ISSNs: 1040-8428

Abstract

Abstract: Background: For over 25 years, there has been a debate revolving around the timing of breast cancer surgery, menstrual cycle, and prognosis. Methods: This systematic review synthesizes and evaluates the body of evidence in an effort to inform evidence-based practice. A keyword and reference search was performed in PubMed and Web of Science to identify human studies that met the inclusion criteria. A total of 58 studies (48 international and 10 U.S.-based) were identified. We provided a narrative summary on study findings and conducted a meta-analysis on a subset of studies where quantitative information was available. Results: Findings from both qualitative and quantitative analyses were inconclusive regarding performing breast cancer surgery around a specific phase of the menstrual cycle. Conclusion: Based on the Institute of Medicine criteria, evidence is insufficient to recommend a change in current primary breast cancer surgery practice based on menstrual phase.