Elastic Abdominal Binders Attenuate Orthostatic Hypotension in Parkinson's Disease. Issue 2 (27th November 2015)

• Record Type: Journal Article
• Authors: Fanciulli, Alessandra; Goebel, Georg; Metzler, Bernhard; Sprenger, Fabienne; Poewe, Werner; Wenning, Gregor K.; Seppi, Klaus
• Is Part Of: Movement disorders clinical practice. Volume 3:Issue 2(2016:Jun.)
• Page Start: 156
• Page End: 160
• Publication Date: 2015-11-27
• Subjects: Parkinson's disease -- orthostatic hypotension -- abdominal binder -- Orthostatic Hypotension Questionnaire (OHQ); Movement Disorders; Movement disorders -- Periodicals; Movement disorders; Periodicals; Periodicals; 616
• DOI: 10.1002/mdc3.12270
• Languages: English
• ISSNs: 2330-1619

Abstract

Abstract: Background and Methods: To investigate the possible efficacy of an elastic abdominal binder to control orthostatic hypotension (OH) associated with Parkinson's disease (PD), 15 patients with PD and OH were enrolled in a single‐blind crossover study with elastic abdominal versus placebo binder on two different days, separated by a 1‐day interval, followed by a 4‐week open‐label follow‐up. Results: Intervention significantly reduced blood pressure fall upon tilting. The mean difference (standard deviation; 95% confidence intervals) between abdominal binder versus placebo was +10 mm Hg (10.2; +3.5, +16.5; P = 0.006). No significant effect on supine mean blood pressure values was observed compared to placebo ( P = 0.3). Symptoms of OH decreased significantly during follow‐up ( P = 0.003), as assessed by means of the Orthostatic Hypotension Questionnaire. Conclusions: Our findings suggest that elastic abdominal binders may be a simple complementary tool to alleviate OH in PD.