Microfluidics‐Assisted Osteogenesis: Injectable Stem Cell‐Laden Photocrosslinkable Microspheres Fabricated Using Microfluidics for Rapid Generation of Osteogenic Tissue Constructs (Adv. Funct. Mater. 17/2016). (May 2016)

• Record Type: Journal Article
• Authors: Zhao, Xin; Liu, Shen; Yildirimer, Lara; Zhao, Hong; Ding, Ruihua; Wang, Huanan; Cui, Wenguo; Weitz, David
• Is Part Of: Advanced functional materials. Volume 26:Number 17(2016)
• Page Start: 2976
• Page End: 2976
• Publication Date: 2016-05
• Subjects: bone marrow‐derived mesenchymal stem cells -- microfluidics -- microspheres -- osteogenesis -- photocrosslinkable gelatin; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201670110
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : A bone regeneration strategy with minimum invasiveness is developed on page 2809 by W. Cui, D. Weitz, and co‐workers, using microfluidics‐fabricated photocrosslinkable gelatin microspheres encapsulating bone marrow‐derived mesenchymal stem cells and growth factors. The cell‐laden microspheres are found to enhance and accelerate osteogenesis in vitro and in vivo, associated with a significant increase in mineralization.