Application of response surface methodology to optimize the treatment of cephems pharmaceutical wastewater by ultrasound/Fenton process. Issue 23 (14th May 2016)

• Record Type: Journal Article
• Authors: Gao, Aifang; Gao, Heng; Zhu, Zhenya; Jiao, Zhen
• Is Part Of: Desalination and water treatment. Volume 57:Issue 23(2016)
• Page Start: 10866
• Page End: 10877
• Publication Date: 2016-05-14
• Subjects: Response surface methodology -- Box–Behnken design -- Cephems pharmaceutical wastewater -- Ultrasound/Fenton; Saline water conversion -- Periodicals; Saline water conversion; Water -- Purification; Periodicals; 628.167
• DOI: 10.1080/19443994.2015.1038737
• Languages: English
• ISSNs: 1944-3994

Abstract

Abstract: Response surface methodology was utilized to optimize the treatment of wastewater from a production of cephem pharmaceuticals using ultrasound/Fenton processes. Box–Behnken design with four variables (initial pH (3, 4, 5), Fe 2+ concentration (0.006, 0.008, 0.010 mol/L), mole ratio of H2 O2 to Fe 2+ (1:1, 2:1, 3:1), and ultrasound power (400, 450, 500 W)) was employed in this study to determine the most efficient combination of these variables for COD removal. The optimum conditions of initial pH, Fe 2+ concentration, mole ratio of H2 O2 to Fe 2+, and ultrasound power were found to be 4.04, 0.008 mol/L, 2:1, and 487 W, respectively, for maximum COD removal efficiency (87.9%). A quadratic model was obtained for COD removal efficiency through this design. The experimental values are in good agreement with predicted values and the model was highly significant with the correlation coefficient of 0.999.