Focused ultrasound to transiently disrupt the blood brain barrier. (June 2016)

• Record Type: Journal Article
• Authors: Mitrasinovic, Stefan; Appelboom, Geoff; Detappe, Alexandre; Sander Connolly, E.
• Is Part Of: Journal of clinical neuroscience. Volume 28(2016:Jun.)
• Page Start: 187
• Page End: 189
• Publication Date: 2016-06
• Subjects: Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2015.12.011
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: First application of MRI-guided Focused Ultrasound to disrupt the BBB on a human patient. The technique is non-invasive, transient and allows BBB disruption to focal regions of interest. Provides potential for a new technique of targeted drug delivery to previously inaccessible brain tissue.