Multichannel Reaction of α‐Bromo­enones with 1, 2‐Diamines: Synthesis of 1, 4‐Diazabicyclo[4.1.0]hept‐4‐enes by Reaction with N‐Unsubstituted 1, 2‐Diamines. Issue 8 (18th February 2016)

• Record Type: Journal Article
• Authors: Muzalevskiy, Vasily M.; Rulev, Alexander Yu.; Kondrashov, Evgeniy V.; Romanov, Alexey R.; Ushakov, Igor A.; Chertkov, Vyacheslav A.; Nenajdenko, Valentine G.
• Is Part Of: European journal of organic chemistry. Issue 8(2016)
• Page Start: 1612
• Page End: 1618
• Publication Date: 2016-02-18
• Subjects: Fluorine -- Nitrogen heterocycles -- Small ring systems -- Ketones -- Cyclization -- Reaction mechanisms; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201501584
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: The reaction of 2‐bromoenones with N ‐unsubstituted 1, 2‐diamines was studied. An easy access to 1, 4‐diazabicyclo[4.1.0]hept‐4‐enes was developed. The multistep mechanism of the reaction is discussed. Final conclusions on the influence of the structure of the starting 2‐bromoenones and 1, 2‐diamines on the direction of the reaction are established. Abstract : The reaction of 2‐bromoenones and 1, 2‐diamines led effectively to 1, 4‐diazabicyclo[4.1.0]hept‐4‐enes.