Catalytic asymmetric dearomatization (CADA) reactions of phenol and aniline derivatives. (22nd January 2016)

• Record Type: Journal Article
• Authors: Wu, Wen-Ting; Zhang, Liming; You, Shu-Li
• Is Part Of: Chemical Society reviews. Volume 45:Number 6(2016:Mar.)
• Page Start: 1570
• Page End: 1580
• Publication Date: 2016-01-22
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cs00356c
• Languages: English
• ISSNs: 0306-0012

Abstract

Abstract : In this tutorial review, an up to date summary of recent progress in catalytic asymmetric dearomatization (CADA) reactions of phenol and aniline derivatives is presented. Abstract : Phenols are widely used as starting materials in both industrial and academic society. Dearomatization reactions of phenols provide an efficient way to construct highly functionalized cyclohexadienones. The main challenge to make them asymmetric by catalytic methods is to control the selectivity while overcoming the loss of aromaticity. In this tutorial review, an up to date summary of recent progress in CADA reactions of phenol and aniline derivatives is presented.