A massive osteonecrosis with Le Fort I-type pathological fracture, caused by bisphosphonate-related osteonecrosis of the jaw (BRONJ): A rare case report. Issue 3 (May 2016)

• Record Type: Journal Article
• Authors: Sukegawa, Shintaro; Kanno, Takahiro; Katase, Naoki; Matsuzaki, Hidenobu; Shibata, Akane; Takahashi, Yuka; Furuki, Yoshihiko
• Is Part Of: Journal of oral and maxillofacial surgery, medicine, and pathology. Volume 28:Issue 3(2016)
• Page Start: 255
• Page End: 258
• Publication Date: 2016-05
• Subjects: Osteonecrosis -- Bisphosphonate -- Pathological fracture; Mouth -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Maxilla -- Surgery -- Periodicals; Oral medicine -- Periodicals; Mouth -- Diseases -- Pathogenesis -- Periodicals; Surgery, Oral -- Periodicals; Oral Medicine -- Periodicals; Pathology, Oral -- Periodicals; Face -- Surgery; Maxilla -- Surgery; Mouth -- Diseases -- Pathogenesis; Mouth -- Surgery; Oral medicine; Electronic journals -- Sciences; Electronic journals -- Medicine; Periodicals; 617.522059
• DOI: 10.1016/j.ajoms.2015.10.001
• Languages: English
• ISSNs: 2212-5566

Abstract

Abstract: Bisphosphonates (BPs) are useful drugs for the management of osteoporosis and metastatic bone disease, and are used to prevent skeletal-related events. However, the side effects of BPs, bisphosphonate-related osteonecrosis of the jaw (BRONJ), sometimes severely impairs patient quality of life. Here we report a case of severe BRONJ in the maxilla, which caused Le Fort I-type fracture-like bone fracture due to formation of a large sequestrum in the maxilla.