Identification of human papillomavirus in pterygium. (12th April 2015)

• Record Type: Journal Article
• Authors: Hamed‐Azzam, Shirin; Edison, Natalia; Briscoe, Daniel; Mukari, Abed; Elmalah, Irit
• Is Part Of: Acta ophthalmologica. Volume 94:Number 3(2016)
• Page Start: e195
• Page End: e197
• Publication Date: 2015-04-12
• Subjects: human papillomavirus -- immunohistochemistry -- pathogenesis of pterygium -- pterygium; Ophthalmology -- Periodicals; 617.7005
• DOI: 10.1111/aos.12729
• Languages: English
• ISSNs: 1755-375X

Abstract

Abstract: Purpose: The purpose of this study was to evaluate the involvement of human papillomavirus in the pathogenesis of primary and recurrent pterygium in northern Israel. Methods: A retrospective study examined 100 randomly chosen pterygium specimens with solar elastosis, from 100 patients who underwent pterygium surgery during 2012–2013 at the Emek Medical Center. All the specimens were analysed for evidence of human papillomavirus infection by immunohistochemistry. Results: Human papillomavirus was not detected in any of the 100 pterygia samples by immunohistochemistry. These used samples were taken from 100 patients with mean age of 51.5 years and a primary: recurrent ratio of 8.09:1. Conclusion: We conclude from our study that human papillomavirus infection does not appear to be an important pathogenic factor of pterygium in Israel.