New Alkaloids and α‐Glucosidase Inhibitory Flavonoids from Ficus hispida. Issue 4 (April 2016)

• Record Type: Journal Article
• Authors: Shi, Zheng‐Feng; Lei, Chun; Yu, Bang‐Wei; Wang, He‐Yao; Hou, Ai‐Jun
• Is Part Of: Chemistry & biodiversity. Volume 13:Issue 4(2016:Apr.)
• Page Start: 445
• Page End: 450
• Publication Date: 2016-04
• Subjects: Ficus hispida -- Alkaloids -- Isoprenylated flavonoids -- α‐Glucosidase; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Biodiversity -- Periodicals; 572
• DOI: 10.1002/cbdv.201500142
• Languages: English
• ISSNs: 1612-1872

Abstract

Abstract : Two new pyrrolidine alkaloids, ficushispimines A (1 ) and B (2 ), a new ω ‐(dimethylamino)caprophenone alkaloid, ficushispimine C (3 ), and a new indolizidine alkaloid, ficushispidine (4 ), together with the known alkaloid5 and 11 known isoprenylated flavonoids6 – 16, were isolated from the twigs of Ficus hispida . Their structures were elucidated by spectroscopic methods. Isoderrone (8 ), 3′‐(3‐methylbut‐2‐en‐1‐yl)biochanin A (11 ), myrsininone A (12 ), ficusin A (13 ), and 4′, 5, 7‐trihydroxy‐6‐[(1 R *, 6 R *)‐3‐methyl‐6‐(1‐methylethenyl)cyclohex‐2‐en‐1‐yl]isoflavone (14 ) showed inhibitory effects on α ‐glucosidase in vitro . Abstract :