An EM algorithm for estimating the destructive weighted Poisson cure rate model. Issue 8 (23rd May 2016)

• Record Type: Journal Article
• Authors: Gallardo, Diego I.; Bolfarine, Heleno; Pedroso-de-Lima, Antonio Carlos
• Is Part Of: Journal of statistical computation and simulation. Volume 86:Issue 8(2016)
• Page Start: 1497
• Page End: 1515
• Publication Date: 2016-05-23
• Subjects: survival analysis -- robustness -- competing risks -- weighted Poisson distribution; Mathematical statistics -- Data processing -- Periodicals; Digital computer simulation -- Periodicals; 519.5028505
• DOI: 10.1080/00949655.2015.1071375
• Languages: English
• ISSNs: 0094-9655

Abstract

Abstract : In this paper, an algorithm is developed to compute estimates for parameters in destructive weighted Poisson cure rate models. It is shown, analytically, the robustness of the procedure with respect to the maximization of the observed likelihood function. The approach allows a simple implementation of different distributions for non-destroyed concurrent causes. The performance of the method is evaluated through simulation studies and by analysing a real data set related to patients with malignant melanoma.