ChemInform Abstract: Recyclable Organocatalyst‐Promoted One‐Pot Asymmetric Synthesis of Spirooxindoles Bearing Multiple Stereogenic Centers. Issue 18 (April 2016)

• Record Type: Journal Article
• Authors: Huang, Xin; Pham, Kenny; Yi, Wenbin; Zhang, Xiaofeng; Clamens, Cecilia; Hyatt, Jeremy H.; Jasinsk, Jerry P.; Tayvah, Uriel; Zhang, Wei
• Is Part Of: ChemInform. Volume 47:Issue 18(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-04
• Subjects: spirocyclic compounds (heterocyclic compounds) -- indole derivatives, isoindole derivatives -- pyridine derivatives -- multicomponent reactions -- ring closure reactions, annulation reactions -- organocatalysis -- diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism); Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201618101
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: A recyclable fluorous bifunctional Cinchona alkaloid/thiourea‐catalyzed, one‐pot four‐component Michael/Mannich/cyclization sequence is developed for the asymmetric synthesis of spirooxindoles containing 2‐piperidinone and tetrahydropyridine rings.