Palladium-catalysed coupling reaction of aminals with N-sulfonyl hydrazones to give allylic sulfones. Issue 2 (6th January 2016)

• Record Type: Journal Article
• Authors: Li, Jiawen; Qin, Guiping; Liu, Yang; Huang, Hanmin
• Is Part Of: Organic chemistry frontiers. Volume 3:Issue 2(2016:Feb.)
• Page Start: 259
• Page End: 267
• Publication Date: 2016-01-06
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c5qo00381d
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : Palladium-catalysed cross-coupling of aminals with N -sulfonyl hydrazones has been established via C–N bond activation under base-free conditions. Abstract : Palladium-catalysed cross-coupling of aminals with N -sulfonyl hydrazones has been established via C–N bond activation under base-free conditions, in which one C–C bond and one C–S bond were simultaneously generated. It was successfully applied in the construction of a variety of aminomethyl substituted allylic sulfones. Preliminary mechanistic studies indicated that the unique electrophilic cyclopalladated complex was involved in the catalytic cycle.