Characterization and hypoglycemic activity of a β-pyran polysaccharides from bamboo shoot (Leleba oldhami Nakal) shells. (25th June 2016)

• Record Type: Journal Article
• Authors: Zheng, Yafeng; Zhang, Shuai; Wang, Qi; Lu, Xu; Lin, Liangmei; Tian, Yuting; Xiao, Jianbo; Zheng, Baodong
• Is Part Of: Carbohydrate polymers. Volume 144(2016)
• Page Start: 438
• Page End: 446
• Publication Date: 2016-06-25
• Subjects: Polysaccharides -- Bamboo shoot shells -- Structural characterization -- Hypoglycemic activity; Polysaccharides -- Periodicals; Polysaccharides -- Periodicals; Polysaccharides -- Périodiques; Electronic journals; 547.78
• DOI: 10.1016/j.carbpol.2016.02.073
• Languages: English
• ISSNs: 0144-8617

Abstract

Graphical abstract: Highlights: A homogeneous highly-branched beta type pyran polysaccharide was isolated from bamboo shoot shells. The polysaccharides from bamboo shoot shell showed hypoglycemic effect in diabetic mice. The polysaccharides improved body weight loss and serum insulin loss. Abstract: The bamboo shoot ( Leleba oldhami Nakal) shell is a by-product during bamboo shoot processing. It is a cheap and available resource for dietary polysaccharides. Herein, a novel polysaccharide BSSP2a was isolated and characterized from the bamboo shoot shell polysaccharides, and it was identified as a homogeneous highly-branched beta type pyran polysaccharide with a molecular weight of 1.63 × 10 4 kDa, which consisted of arabinose, xylose, mannose, glucose and galactose at a molar ratio of 20.4:4.9:1:3.4:20.6. The crude polysaccharides (BSSP) from the bamboo shoots shell showed hypoglycemic activity on the high fat diet and streptozotocin induced diabetic mice in a dose-dependent manner. The administration of high dose BSSP (400 mg/kg) improved body weight loss and serum insulin loss, and significantly decreased the blood glucose level, serum triglycerides as well as total cholesterol levels by 48.7%, 34.8% and 26.5%, respectively. The results highlight the potential of the bamboo shoot shell polysaccharides as a natural anti-diabetic agent.