Antibacterial and catecholase activities of Co(III) and Ni(II) Schiff base complexes. (9th March 2016)

• Record Type: Journal Article
• Authors: Ghosh, Ayon Kanti; Mitra, Merry; Fathima, Aafreen; Yadav, Hareram; Roy Choudhury, Angshuman; Nair, Balachandran Unni; Ghosh, Rajarshi
• Is Part Of: Polyhedron. Volume 107(2016)
• Page Start: 1
• Page End: 8
• Publication Date: 2016-03-09
• Subjects: Cobalt -- Nickel -- Schiff base -- Antibacterial activity -- Catecholase activity; Chemistry, Inorganic -- Periodicals; Chimie inorganique -- Périodiques; Organometaalverbindingen; Anorganische chemie; 546.05
• DOI: 10.1016/j.poly.2016.01.015
• Languages: English
• ISSNs: 0277-5387

Abstract

Graphical abstract: X-ray structural analyses of two newly synthesized Schiff base-complexes, [Co(L)3 ] (1 ) and [Ni(L)2 ] (2 ) [HL = 2-(( E )-(2-pyridine-2-pyridin-2-ylthio)ethylimino)methyl)phenol], reveal the bidentate chelation behavior of the ligand HL with octahedral and square planar geometries at the metal centers in1 and2, respectively. Both the compounds show antibacterial activity as well as catecholase activity. The antibacterial activities of the compounds were investigated on gram positive and gram negative bacteria; compound2 was found to be better in terms of antibacterial activity than1 against both the bacteria. Moreover, both compounds catalyse the oxidation of 3, 5-ditertiarybutylcatechol in methanol in the presence of molecular oxygen with first order reaction kinetics and turn over numbers 3.48 × 10 3 h −1 (1 ) and 2.68 × 10 3 h −1 (2 ). Abstract: X-ray structural analyses of two newly synthesized Schiff base-complexes, [Co(L)3 ] (1 ) and [Ni(L)2 ] (2 ) [HL = 2-(( E )-(2-pyridine-2-pyridin-2-ylthio)ethylimino)methyl)phenol], reveal the bidentate chelation behavior of the ligand HL with octahedral and square planar geometries at the metal centers in1 and2, respectively. Both the compounds show antibacterial activity as well as catecholase activity. The antibacterial activities of the compounds were investigated on gram positive and gram negative bacteria; compound2 was found to be better in terms of antibacterial activity than1 against both the bacteria. Moreover, both compounds catalyse the oxidation of 3, 5-ditertiarybutylcatechol in methanol in the presence of molecular oxygen with first order reaction kinetics and turn over numbers 3.48 × 10 3 h −1 (1 ) and 2.68 × 10 3 h −1 (2 ).